Spinning Disc Microscope

The Leiden Institute of Chemistry wishes to purchase a Spinning Disc microscope. The primary tasks of this setup is to image live zebrafish larvae (0 to 12 days post fertilization) and to image (i.e. brightfield and fluorescence imaging) biological samples (cells, organoids, tissue (sections), organs like the brain of zebrafish) …

CPV: 38510000 Microscopes, 38634000 Optical microscopes
Deadline:
Jan. 21, 2025, 11 a.m.
Deadline type:
Submitting a bid
Place of execution:
Spinning Disc Microscope
Awarding body:
Universiteit Leiden
Award number:
T120687

1. Buyer

1.1 Buyer

Official name : Universiteit Leiden
Legal type of the buyer : Body governed by public law
Activity of the contracting authority : Education

2. Procedure

2.1 Procedure

Title : Spinning Disc Microscope
Description : The Leiden Institute of Chemistry wishes to purchase a Spinning Disc microscope. The primary tasks of this setup is to image live zebrafish larvae (0 to 12 days post fertilization) and to image (i.e. brightfield and fluorescence imaging) biological samples (cells, organoids, tissue (sections), organs like the brain of zebrafish) before and after expansion using published Expansion Microscopy (ExM) protocols with high speed, sensitivity and resolution. Our spinning disc microscope is intended to be used to image large numbers of zebrafish larvae at different developmental stages before and after injection of nanomedicines/drugs in the blood stream or directly into tissue/organs like the brain. The microscope should be able to image this in brightfield or using fluorescence with high speed, sensitivity and resolution.   The spinning disc microscope will also be used to image cells, organoids, tissue (sections), organs like the brain of zebrafish before and after expansion of the biological sample. In the expanded state the density of fluorescent probes is very low and therefore a high sensitivity is required. Furthermore, these samples are similar to the zebrafish large in size (multiple mm tot cm in length) requiring a fastmode of imaging. The microscope will be used by light microscopy experts from the cell observatory and by selected postdoctoral students and PhD-students after receiving initial training by permanent staff with many years of experience on light microscopy. About Leiden University Leiden University, founded in 1575, is one of Europe's leading international research universities. The university has seven faculties in the humanities, sciences and gamma domains, is located in Leiden and The Hague and has 6,700 employees and approximately 30,000 students. Her motto is Praesidium Libertatis - Stronghold of Freedom. Procedure Registration takes place via the Mercell Source-to-Contract platform. You will find the questionnaire for this tender under the 'Request for Quotation' button. In this questionnaire you will find all questions that need to be answered. In order to be able to submit your quotation in full, you must also complete the price list in its entirety. For system technical questions, you can consult the support database via Mercell's database. If you cannot find the desired result here, you can also find the contact details of the Mercell Service Desk here.
Procedure identifier : 5c8b3a7c-e9ff-414b-871e-53ec3d1e5d39
Previous notice : 99445-2024
Internal identifier : T120687
Type of procedure : Open
The procedure is accelerated : no
Justification for the accelerated procedure :
Main features of the procedure :

2.1.1 Purpose

Main nature of the contract : Supplies
Main classification ( cpv ): 38510000 Microscopes
Additional classification ( cpv ): 38634000 Optical microscopes

2.1.2 Place of performance

Country subdivision (NUTS) : Agglomeratie Leiden en Bollenstreek ( NL337 )
Country : Netherlands
Additional information : See documentation

2.1.3 Value

Estimated value excluding VAT : 450 000 Euro

2.1.4 General information

Legal basis :
Directive 2014/24/EU

2.1.6 Grounds for exclusion

Analogous situation like bankruptcy under national law : See § 2.3.5.1. Aanbestedingswet 2012
Bankruptcy : See § 2.3.5.1. Aanbestedingswet 2012
Corruption : See § 2.3.5.1. Aanbestedingswet 2012
Arrangement with creditors : See § 2.3.5.1. Aanbestedingswet 2012
Participation in a criminal organisation : See § 2.3.5.1. Aanbestedingswet 2012
Agreements with other economic operators aimed at distorting competition : See § 2.3.5.1. Aanbestedingswet 2012
Breaching of obligations in the fields of environmental law : See § 2.3.5.1. Aanbestedingswet 2012
Money laundering or terrorist financing : See § 2.3.5.1. Aanbestedingswet 2012
Fraud : See § 2.3.5.1. Aanbestedingswet 2012
Child labour and other forms of trafficking in human beings : See § 2.3.5.1. Aanbestedingswet 2012
Insolvency : See § 2.3.5.1. Aanbestedingswet 2012
Breaching of obligations in the fields of labour law : See § 2.3.5.1. Aanbestedingswet 2012
Assets being administered by liquidator : See § 2.3.5.1. Aanbestedingswet 2012
Guilty of misrepresentation, withheld information, unable to provide required documents and obtained confidential information of this procedure : See § 2.3.5.1. Aanbestedingswet 2012
Conflict of interest due to its participation in the procurement procedure : See § 2.3.5.1. Aanbestedingswet 2012
Direct or indirect involvement in the preparation of this procurement procedure : See § 2.3.5.1. Aanbestedingswet 2012
Early termination, damages or other comparable sanctions : See § 2.3.5.1. Aanbestedingswet 2012
Breaching of obligations in the fields of social law : See § 2.3.5.1. Aanbestedingswet 2012
Payment of social security contributions : See § 2.3.5.1. Aanbestedingswet 2012
Business activities are suspended : See § 2.3.5.1. Aanbestedingswet 2012
Payment of taxes : See § 2.3.5.1. Aanbestedingswet 2012
Terrorist offences or offences linked to terrorist activities : See § 2.3.5.1. Aanbestedingswet 2012

5. Lot

5.1 Lot technical ID : LOT-0000

Title : Spinning Disc Microscope
Description : The Leiden Institute of Chemistry wishes to purchase a Spinning Disc microscope. The primary tasks of this setup is to image live zebrafish larvae (0 to 12 days post fertilization) and to image (i.e. brightfield and fluorescence imaging) biological samples (cells, organoids, tissue (sections), organs like the brain of zebrafish) before and after expansion using published Expansion Microscopy (ExM) protocols with high speed, sensitivity and resolution. Our spinning disc microscope is intended to be used to image large numbers of zebrafish larvae at different developmental stages before and after injection of nanomedicines/drugs in the blood stream or directly into tissue/organs like the brain. The microscope should be able to image this in brightfield or using fluorescence with high speed, sensitivity and resolution.   The spinning disc microscope will also be used to image cells, organoids, tissue (sections), organs like the brain of zebrafish before and after expansion of the biological sample. In the expanded state the density of fluorescent probes is very low and therefore a high sensitivity is required. Furthermore, these samples are similar to the zebrafish large in size (multiple mm tot cm in length) requiring a fastmode of imaging. The microscope will be used by light microscopy experts from the cell observatory and by selected postdoctoral students and PhD-students after receiving initial training by permanent staff with many years of experience on light microscopy. About Leiden University Leiden University, founded in 1575, is one of Europe's leading international research universities. The university has seven faculties in the humanities, sciences and gamma domains, is located in Leiden and The Hague and has 6,700 employees and approximately 30,000 students. Her motto is Praesidium Libertatis - Stronghold of Freedom. Procedure Registration takes place via the Mercell Source-to-Contract platform. You will find the questionnaire for this tender under the 'Request for Quotation' button. In this questionnaire you will find all questions that need to be answered. In order to be able to submit your quotation in full, you must also complete the price list in its entirety. For system technical questions, you can consult the support database via Mercell's database. If you cannot find the desired result here, you can also find the contact details of the Mercell Service Desk here.
Internal identifier : T120687

5.1.1 Purpose

Main nature of the contract : Supplies
Main classification ( cpv ): 38510000 Microscopes
Additional classification ( cpv ): 38634000 Optical microscopes

5.1.2 Place of performance

Country subdivision (NUTS) : Agglomeratie Leiden en Bollenstreek ( NL337 )
Country : Netherlands
Additional information : See documentation

5.1.3 Estimated duration

Other duration : Unknown

5.1.5 Value

Estimated value excluding VAT : 450 000 Euro

5.1.6 General information

Reserved participation : Participation is not reserved.
Procurement Project fully or partially financed with EU Funds.
Information about European Union funds
EU funds programme : Horizon Europe – the Framework Programme for Research and Innovation (2021/2027)
Identifier of EU funds : 101118999 Cat4CanCenter
Further details of EU funds : Catalysis for Cancer Treatment ERC-2023-SYG
The procurement is covered by the Government Procurement Agreement (GPA) : yes

5.1.9 Selection criteria

Criterion :
Type : Economic and financial standing
Name : Insurance
Description : €1,000,000 against legal liability and against professional and corporate liability
Use of this criterion : Used
Criterion :
Type : Other
Use of this criterion : Not used
Criterion :
Type : Suitability to pursue the professional activity
Use of this criterion : Not used
Criterion :
Type : Technical and professional ability
Name : Compentences
Description : 1. Tenderer must have an extensive track record in supplying high performance spinning disc microscopes. 2. Tender must possess the competence of designing, building, installing and maintaining spinning disc microscopes capable of imaging cell culture, organoids, expanded tissue and zebrafish.
Use of this criterion : Used

5.1.10 Award criteria

Criterion :
Type : Quality
Name : Photo activation module
Description : The instrument will have the possibility to connect photo activation module
Weight (points, exact) : 2
Criterion :
Type : Quality
Name : Multi magnification imaging
Description : The instrument will have the possibility to have multi magnification imaging.
Weight (points, exact) : 10
Criterion :
Type : Quality
Name : Filter for each fluorophore
Description : The instrument can have a unique filter for each fluorophore in the list above, for optimal imaging without spectral bleed through.
Weight (points, exact) : 5
Criterion :
Type : Quality
Name : Ease of use
Description : The instrument should be easy to use by (non-expert) scientists after they received (initial) training by expert user.
Weight (points, exact) : 8
Criterion :
Type : Quality
Name : Sample loading
Description : Sample loading (i.e. zebrafish larvae, expanded cells, tissue, organoids, organs) should be possible.
Weight (points, exact) : 8
Criterion :
Type : Quality
Name : Water dispenser system
Description : The instrument should have automatic water dispenser system on all long W.D. objectives.
Weight (points, exact) : 5
Criterion :
Type : Quality
Name : Illumination
Description : The evenness of illumination on max field of view.
Weight (points, exact) : 8
Criterion :
Type : Quality
Name : Speed of acquisition
Description : The speed of acquisition over a set range of the sample.
Weight (points, exact) : 10
Criterion :
Type : Quality
Name : Quality of the obtained images
Description : For cell tissue samples, the quality of the obtained images, with respect to signal intensity, as well as signal to noise.
Weight (points, exact) : 10
Criterion :
Type : Quality
Name : Quality of the obtained images
Description : For cell tissue samples, the quality of the obtained images, with respect to signal intensity, as well as signal to noise.
Weight (points, exact) : 10
Description of the method to be used if weighting cannot be expressed by criteria :
Justification for not indicating the weighting of the award criteria :

5.1.11 Procurement documents

Languages in which the procurement documents are officially available : English
Deadline for requesting additional information : 03/01/2025 11:00 +00:00
Address of the procurement documents : https://s2c.mercell.com/today/120687

5.1.12 Terms of procurement

Terms of submission :
Electronic submission : Required
Languages in which tenders or requests to participate may be submitted : English, Dutch
Electronic catalogue : Not allowed
Variants : Not allowed
Deadline for receipt of tenders : 21/01/2025 11:00 +00:00
Deadline until which the tender must remain valid : 90 Day
Information about public opening :
Opening date : 21/01/2025 11:05 +00:00
Place : Leiden
Additional information : Electronically.
Terms of contract :
The execution of the contract must be performed within the framework of sheltered employment programmes : No
A non-disclosure agreement is required : no
Electronic invoicing : Required
Electronic ordering will be used : yes
Electronic payment will be used : yes
Information about review deadlines : Within 20 days after contract-award decision.

5.1.15 Techniques

Framework agreement :
No framework agreement
Information about the dynamic purchasing system :
No dynamic purchase system
Electronic auction : no

5.1.16 Further information, mediation and review

Review organisation : Rechtbank Den Haag
Organisation receiving requests to participate : Universiteit Leiden
Organisation processing tenders : Universiteit Leiden

8. Organisations

8.1 ORG-0001

Official name : Universiteit Leiden
Registration number : 27368929
Postal address : Kolffpad 1
Town : Leiden
Postcode : 2333BN
Country subdivision (NUTS) : Agglomeratie Leiden en Bollenstreek ( NL337 )
Country : Netherlands
Contact point : Govert Schipperheijn
Telephone : +31715273304
Roles of this organisation :
Buyer
Organisation receiving requests to participate
Organisation processing tenders

8.1 ORG-0002

Official name : Rechtbank Den Haag
Registration number : 82946175
Department : Civiel
Postal address : Postbus 20303
Town : Den Haag
Postcode : 2500 EH
Country subdivision (NUTS) : Agglomeratie ’s-Gravenhage ( NL332 )
Country : Netherlands
Contact point : Informatie
Telephone : +31883622200
Roles of this organisation :
Review organisation

10. Change

Version of the previous notice to be changed : e075389a-da35-4f80-b22b-fbc7e5f0ae5d-01
Main reason for change : Buyer correction
Description : EU funds information added.

10.1 Change

Section identifier : LOT-0000
Description of changes : No changes at this section.

11. Notice information

11.1 Notice information

Notice identifier/version : 6d3337b3-ab20-4046-9e2b-3683a53ac1a9 - 01
Form type : Competition
Notice type : Contract or concession notice – standard regime
Notice dispatch date : 18/11/2024 12:22 +00:00
Notice dispatch date (eSender) : 18/11/2024 12:22 +00:00
Languages in which this notice is officially available : English

11.2 Publication information

Notice publication number : 00705053-2024
OJ S issue number : 225/2024
Publication date : 19/11/2024